Dietary supplements for benign prostatic hyperplasia: an overview of systematic reviews.
- 2012-11
- Maturitas 73(3)
- Tae-Hun Kim
- Hyun-Ja Lim
- Myung-Sunny Kim
- Myeong Soo Lee
- PubMed: 22883375
- DOI: 10.1016/j.maturitas.2012.07.007
Study Design
- Type
- Review
- Population
- older men with benign prostatic hyperplasia (BPH)
- Methods
- Searched 5 electronic databases and relevant overviews without limitations on language or publication status; included 6 systematic reviews of 195 articles
Benign prostatic hyperplasia (BPH) is a common chronic condition in older men. The aim of this overview of systematic reviews (SRs) is to summarise the current evidence on the efficacy and adverse effects of dietary supplements for treating BPH with lower urinary tract symptoms. We searched 5 electronic databases and relevant overviews without limitations on language or publication status. Six SRs of 195 articles were included in this overview. Serenoa repens was reviewed in 3 studies and no specific effect on BPH symptoms and urinary flow measures was observed. However, β-sitosterol, Pygeum africannum and Cernilton were reviewed in one study each, and significant improvement was observed for all three. All the included compounds have mild and infrequent adverse effects. SRs on β-sitosterol, Pygeum africannum and Cernilton have not been updated since 2000, thus an update of reviews on these compounds will be necessary in the future.
Research Insights
Serenoa repens was reviewed in 3 studies and no specific effect on BPH symptoms and urinary flow measures was observed.
- Effect
- Neutral
- Effect size
- Small
Serenoa repens was reviewed in 3 studies and no specific effect on BPH symptoms and urinary flow measures was observed.
- Effect
- Neutral
- Effect size
- Small
Adverse Events Reported
All the included compounds have mild and infrequent adverse effects.
- Finding
- Reported
- Grade
- mild