Acetyl-Carnitine and Improved 6-minute Walking Distance

• Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.

  • 2022-10
  • RCT · n = 92
  • Current pharmaceutical design 28(38)
  • • Giulia Malaguarnera
    • Vito Emanuele Catania
    • Gaetano Bertino
    • Laura Maria Chisari
    • Maria Castorina
    • Claudia Bonfiglio
    • Omar Cauli
    • Michele Malaguarnera

  • PubMed: 36043711
  • DOI: 10.2174/1381612828666220830092815

  4 Insights on

  • Improved 6-minute Walking Distance

  • High evidence
  • Clinical

  increase in 6-walking distance (p < 0.0001); ALCAR group vs. placebo group showed an increase in the 6-walking distance (p < 0.001)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  1.5 g BID