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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Acetyl-Carnitine and Improved Forced Vital Capacity

Doses used in studies

g/day: 3 (median 3, IQR 3–3) — 1 study

Time to effect

Median: 24.3 months · IQR 24.3 months–24.3 months · Range 24.3 months–24.3 months — Reported in 1 of 1 study

1 of 1 paper

Retrospective observational study on the use of acetyl-L-carnitine in ALS.
- 2023-06-28
- Observational · n = 45
- Journal of neurology 270(11)
- - Serena Sassi
  - Elisa Bianchi
  - Luca Diamanti
  - Danilo Tornabene
  - Elisabetta Sette
  - Doriana Medici
  - Sabrina Matà
  - Deborah Leccese
  - Martina Sperti
  - Ilaria Martinelli
  - Andrea Ghezzi
  - Jessica Mandrioli
  - Valentina Virginia Iuzzolino
  - Raffaele Dubbioso
  - Francesca Trojsi
  - Carla Passaniti
  - Giulia D'Alvano
  - Massimiliano Filosto
  - Alessandro Padovani
  - Letizia Mazzini
  - Fabiola De Marchi
  - Lucia Zinno
  - Andi Nuredini
  - Paolo Bongioanni
  - Cristina Dolciotti
  - Elena Canali
  - Giulia Toschi
  - Antonio Petrucci
  - Alessia Perna
  - Vittorio Riso
  - Maurizio Inghilleri
  - Laura Libonati
  - Chiara Cambieri
  - Elisabetta Pupillo
- PubMed: 37378756
- DOI: 10.1007/s00415-023-11844-6
5 Insights on
- Improved Forced Vital Capacity
- Moderate evidence
- Clinical
No statistically significant differences were detected in ALSFRS nor FVC nor self-sufficiency.
Effect
Neutral
Effect size
Small
Significant
No
Dose
3 g/day