Acetyl-Carnitine and Improved Self-Sufficiency

• Retrospective observational study on the use of acetyl-L-carnitine in ALS.

  • 2023-06-28
  • Observational · n = 45
  • Journal of neurology 270(11)
  • • Serena Sassi
    • Elisa Bianchi
    • Luca Diamanti
    • Danilo Tornabene
    • Elisabetta Sette
    • Doriana Medici
    • Sabrina Matà
    • Deborah Leccese
    • Martina Sperti
    • Ilaria Martinelli
    • Andrea Ghezzi
    • Jessica Mandrioli
    • Valentina Virginia Iuzzolino
    • Raffaele Dubbioso
    • Francesca Trojsi
    • Carla Passaniti
    • Giulia D'Alvano
    • Massimiliano Filosto
    • Alessandro Padovani
    • Letizia Mazzini
    • Fabiola De Marchi
    • Lucia Zinno
    • Andi Nuredini
    • Paolo Bongioanni
    • Cristina Dolciotti
    • Elena Canali
    • Giulia Toschi
    • Antonio Petrucci
    • Alessia Perna
    • Vittorio Riso
    • Maurizio Inghilleri
    • Laura Libonati
    • Chiara Cambieri
    • Elisabetta Pupillo

  • PubMed: 37378756
  • DOI: 10.1007/s00415-023-11844-6

  5 Insights on

  • Improved Self-Sufficiency

  • Moderate evidence
  • Clinical

  No statistically significant differences were detected in ALSFRS nor FVC nor self-sufficiency.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  3 g/day