Acetyl-L-carnitine for patients with hepatic encephalopathy.
- 2019-01-05
- Meta-Analysis · n = 398
- The Cochrane database of systematic reviews 2019(1)
- Arturo J Martí-Carvajal
- Christian Gluud
- Ingrid Arevalo-Rodriguez
- Cristina Elena Martí-Amarista
- PubMed: 30610762
- DOI: 10.1002/14651858.cd011451.pub2
- High evidence
- Clinical
Meta-analysis showed a reduction in blood ammonium levels favouring acetyl-L-carnitine versus placebo (MD -13.06 mg/dL, 95% CI -17.24 to -8.99; 387 participants; 5 trials; very low-quality evidence).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes