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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Acetyl-Carnitine and Reduced Luteinizing Hormone Level

Doses used in studies

mg/day: 3,000 (median 3,000, IQR 3,000–3,000) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 1 study

1 of 1 paper

Acetyl-L-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial.
- 2021-05-28
- RCT · n = 147
- Advances in therapy 38(7)
- - Saman Tauqir
  - Momina Israr
  - Bushra Rauf
  - Muhammad Omar Malik
  - Syed Hamid Habib
  - Fawad Ali Shah
  - Muhammad Usman
  - Muhammad Asif Raza
  - Inayat Shah
  - Haroon Badshah
  - Ehtesham Ehtesham
  - Mohsin Shah
- PubMed: 34047916
- DOI: 10.1007/s12325-021-01789-5
9 Insights on
- Reduced Luteinizing Hormone Level
- High evidence
- Large Human Trial
- Clinical
LH also decreased in both groups; however, the change was significant only in the combo (metformin plus pioglitazone plus ALC) group (p = 0.013).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
1500 mg twice daily