Carnosine and Increased Appendicular Lean Mass

Doses used in studies

g/day: 2 (median 2, IQR 2–2) — 1 study

Time to effect

Median: 3.3 months · IQR 3.3 months–3.3 months · Range 3.3 months–3.3 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
The abstract does not report any adverse events, side effects, or tolerability statements. It only reports efficacy outcomes (muscle strength, body composition, bone health) and concludes no effect.
from: The Effect of Carnosine Supplementation on Musculoskeletal Health in Adults with Prediabet

1 of 1 paper

The Effect of Carnosine Supplementation on Musculoskeletal Health in Adults with Prediabetes and Type 2 Diabetes: A Secondary Analysis of a Randomized Controlled Trial.

2024-12-15
RCT · n = 49
Nutrients 16(24)
- Saeede Saadati
- Paul Jansons
- David Scott
- Maximilian de Courten
- Aya Mousa
- Jack Feehan
- Jakub Mesinovic
- Barbora de Courten

PubMed: 39770949
DOI: 10.3390/nu16244328

10 Insights on

Increased Appendicular Lean Mass

High evidence
Rigorous Journal
Clinical

Change in appendicular lean mass, percentage of body fat, visceral fat area, proximal tibial cortical volumetric bone mineral density (vBMD), distal tibial trabecular vBMD, and stress-strain index did not differ with carnosine compared to placebo.

Effect: Neutral
Effect size: Small
Significant: No
Dose: 2 g/day