Gamma-Aminobutyric Acid and Delayed Onset of Type 1 Diabetes Mellitus

• Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update.

  • 2024-06-30
  • Review
  • Annals of pediatric endocrinology & metabolism 29(3)
  • • Jane Carissa Sutedja
    • Bryan Gervais de Liyis
    • Made Ratna Saraswati

  • PubMed: 38956751
  • DOI: 10.6065/apem.2346184.092

  1 Insight on

  • Delayed Onset of Type 1 Diabetes Mellitus

  • Low evidence
  • Children

  This review aimed to assess the use of gamma-aminobutyric acid (GABA) to delay the onset of T1DM in children. [...] These findings demonstrate promising results for the use of GABA treatment to delay T1DM, specifically in genetically predisposed children, through immunoregulatory effects and the ability to induce β-cell proliferation.

  Effect

  Beneficial

  Effect size

  Small