A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes.
- 2022-12-24
- RCT · n = 97
- Nature communications 13(1)
- Alexandra Martin
- Gail J Mick
- Heather M Choat
- Alison A Lunsford
- Hubert M Tse
- Gerald G McGwin
- Kenneth L McCormick
- PubMed: 36566274
- DOI: 10.1038/s41467-022-35544-3
- High evidence
- Rigorous Journal
- Children
the combination GABA/GAD reduced fasting and meal-stimulated serum glucagon
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- oral GABA twice-daily (dose not specified in abstract)