Gamma-Aminobutyric Acid and Reduced Hemoglobin A1c

Doses used in studies

Time to effect

Median: 6 months · IQR 6 months–6 months · Range 6 months–6 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
Most elevations were, however, transient with no dose-differences.
from: Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in l
elevated aspartate aminotransferaseReported
Safety concerns included elevated aspartate aminotransferase (AST) in nine subjects, leading to the withdrawal of two subjects.
from: Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in l

1 of 1 paper

Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial.