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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Arginine and Improved Ankle-Brachial Index

Doses used in studies

g/day: 6 (median 6, IQR 6–6) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
No significant effects were observed on ABI (right or left) or on cholesterol and triglyceride concentrations.
from: Assessment of the effectiveness and safety of two-month oral supplementation with L-argini

1 of 1 paper

Assessment of the effectiveness and safety of two-month oral supplementation with L-arginine depending on the type of lipid metabolism disorder in patients with atherosclerotic lower limb ischemia.
- 2025-10-01
- RCT · n = 100
- Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 76(5)
- - M Micker
  - N Balcer-Dymel
  - M Czerwonka
  - B Madej
  - E Swiecka
  - P A Kolodziejski
  - E Pruszynska-Oszmalek
  - Z Checinska-Maciejewska
  - H Krauss
  - A Rekas-Dudziak
- PubMed: 41364169
- DOI: 10.26402/jpp.2025.5.05
8 Insights on
- Improved Ankle-Brachial Index
- High evidence
- Large Human Trial
- Clinical
No significant effects were observed on ABI (right or left) ...
Effect
Neutral
Effect size
Small
Significant
No
Dose
6 g/day