Clinical Study to Evaluate the Possible Efficacy and Safety of L-Arginine in Children with Sickle Cell Disease and Increased Tricuspid Regurgitant Jet Velocity: a Randomized Controlled Trial.
- 2025-06-17
- RCT · n = 50
- Paediatric drugs 27(5)
- Dalia A Gomaa
- Sahar M El-Haggar
- Mohamed R El-Shanshory
- Osama El-Razaky
- Dalia R El-Afify
- PubMed: 40526198
- DOI: 10.1007/s40272-025-00701-w
- High evidence
- Clinical
The abstract reports that LDH levels were assessed at baseline and after 3 months, but no significant difference between groups was explicitly mentioned in the results summary for LDH.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 0.1-0.2 g/kg/day