L-Arginine and Reduced Oral Mucositis Severity

• L-arginine vs. L-glutamine oral suspensions for radiation-induced oral mucositis: a triple-blind randomized trial.

  • 2025-07-03
  • RCT · n = 23
  • Journal of cancer research and clinical oncology 151(7)
  • • Fatma E A Hassanein
    • Christine Mikhail
    • Sarah Elkot
    • Asmaa Abou-Bakr

  • PubMed: 40603739
  • DOI: 10.1007/s00432-025-06213-x

  4 Insights on

  • Reduced Oral Mucositis Severity

  • High evidence
  • Clinical

  WHO scale scores differed significantly among groups (p < 0.001), with arginine and glutamine groups exhibiting lower mucositis severity than the maltodextrin group.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  5 g