L-Arginine and Reduced Oxygen Support Requirement

• The effect of l-arginine supplementation on amelioration of oxygen support in severe COVID-19 pneumonia.

  • 2022-12
  • RCT · n = 74
  • Clinical nutrition ESPEN 52
  • • Jananee Muralidharan
    • Sindhu Kashyap
    • Poorvikha S
    • Mathew Jacob
    • Anjali Ollapally
    • Jyothi Idiculla
    • John Michael Raj
    • Tinku Thomas
    • Anura V Kurpad

  • PubMed: 36513483
  • DOI: 10.1016/j.clnesp.2022.09.024

  3 Insights on

  • Reduced Oxygen Support Requirement

  • High evidence
  • Clinical

  At end of the study, 28 patients (73.6%) in l-Arg and 26 patients (72.2%) in the placebo group were weaned off oxygen support.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  3 g daily