Interventions for treating leg ulcers in people with sickle cell disease.
- 2021-01-09
- Systematic Review · n = 198
- The Cochrane database of systematic reviews 2021(1)
- Arturo J Martí-Carvajal
- Jennifer M Knight-Madden
- Maria José Martinez-Zapata
- PubMed: 34559425
- DOI: 10.1002/14651858.cd008394.pub4
- High evidence
- Clinical
Three trials reported on complete leg ulcer closure (isoxsuprine, arginine butyrate, RGD peptide matrix; very low quality of evidence). None reported a clinical benefit.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No