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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Carnitine and Increased Platelet Count

Doses used in studies

g/day: 3 (median 3, IQR 3–3) — 1 study

Time to effect

Median: 3.1 months · IQR 7.2 weeks–4.6 months · Range 7 days–6 months — Reported in 2 of 2 studies

2 of 2 papers

The effects of L-carnitine supplementation on inflammation, oxidative stress, and clinical outcomes in critically Ill patients with sepsis: a randomized, double-blind, controlled trial.
- 2024-03-06
- RCT · n = 60
- Nutrition journal 23(1)
- - Mahdi Keshani
  - Babak Alikiaii
  - Zahra Babaei
  - Gholamreza Askari
  - Zahra Heidari
  - Manoj Sharma
  - Mohammad Bagherniya
- PubMed: 38444016
- DOI: 10.1186/s12937-024-00934-4
9 Insights on
- Increased Platelet Count
- High evidence
- Clinical
increase in platelet (p: 0.004) significantly
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
3 g/day
Impact of L-carnitine supplementation on post-transplant outcomes in liver transplant candidates with sarcopenia: A randomized controlled open-label trial.
- 2025-12
- RCT · n = 18
- Clinical nutrition ESPEN 70
- - Marwa Abd El-Razek Salama
  - Elham Ahmed Hassan
  - Nahed A Makhlouf
- PubMed: 40962224
- DOI: 10.1016/j.clnesp.2025.09.008
2 Insights on
- Increased Platelet Count
- High evidence
- Clinical
Sarcopenic patients receiving L-carnitine showed significant post-transplant improvements in ... biochemical markers (INR, albumin, bilirubin, platelets).
Effect
Beneficial
Effect size
Moderate
Significant
Yes