L-Carnitine and Increased Sperm Concentration

• The efficacy of combined l-carnitine and l-acetyl carnitine in men with idiopathic oligoasthenoteratozoospermia: A systematic review and meta-analysis.

  • 2019-11-07
  • Meta-Analysis · n = 693
  • Andrologia 52(2)
  • • Xuebao Zhang
    • Yuanshan Cui
    • Liying Dong
    • Miao Sun
    • Yong Zhang

  • PubMed: 31701550
  • DOI: 10.1111/and.13470

  7 Insights on

  • Increased Sperm Concentration

  • High evidence
  • Clinical

  no significant differences were found in other semen indicators between the two groups

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Meta-analysis of the efficacy and safety of L-carnitine and N-acetylcysteine monotherapy for male idiopathic infertility.

  • 2025
  • Meta-Analysis
  • Revista internacional de andrologia 23(1)
  • • Xiaohong Ma
    • Yingying Yang
    • Shiguo Liu
    • Yuanshan Cui
    • Jitao Wu

  • PubMed: 40350672
  • DOI: 10.22514/j.androl.2025.004

  6 Insights on

  • Increased Sperm Concentration

  • High evidence

  NAC improved the first three indicators (sperm concentration, normal morphology, sperm motility) while also increasing ejaculation volume (p = 0.002)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes