L-Carnitine and Reduced Hemoglobin A1c

• The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials.

  • 2024-05
  • Meta-Analysis · n = 2,041
  • Clinical therapeutics 46(5)
  • • Amin Mirrafiei
    • Ahmad Jayedi
    • Sakineh Shab-Bidar

  • PubMed: 38594107
  • DOI: 10.1016/j.clinthera.2024.03.002

  6 Insights on

  • Reduced Hemoglobin A1c

  • High evidence
  • Clinical

  HbA1c (MD: -0.16%, 95% CI: -0.32, -0.01; I2 = 94%, n = 18, GRADE = moderate)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  1 g/day

• The effects of L-carnitine supplementation on cardiovascular risk factors in participants with impaired glucose tolerance and diabetes: a systematic review and dose-response meta-analysis.

  • 2024-07-31
  • Review · n = 2,900
  • Diabetology & metabolic syndrome 16(1)
  • • Rezvan Gheysari
    • Mahlagha Nikbaf-Shandiz
    • Amir Mehdi Hosseini
    • Niloufar Rasaei
    • Shabnam Hosseini
    • Hossein Bahari
    • Omid Asbaghi
    • Samira Rastgoo
    • Kian Goudarzi
    • Farideh Shiraseb
    • Reza Behmadi

  • PubMed: 39085907
  • DOI: 10.1186/s13098-024-01415-8

  11 Insights on

  • Reduced Hemoglobin A1c

  • High evidence

  L-carnitine supplementation had a significant effect on HbA1c (WMD = -0.37%, p = 0.013)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes