L-Carnitine and Reduced Hospitalization Rate

• Additional L-Carnitine Reduced the Risk of Hospitalization in Patients with Overt Hepatic Encephalopathy on Rifaximin.

  • 2021-06-28
  • RCT · n = 42
  • Digestive diseases (Basel, Switzerland) 40(3)
  • • Kousuke Kubota
    • Haruki Uojima
    • Xue Shao
    • Shuichiro Iwasaki
    • Hisashi Hidaka
    • Naohisa Wada
    • Takahide Nakazawa
    • Akitaka Shibuya
    • Makoto Kako
    • Wasaburo Koizumi

  • PubMed: 34348263
  • DOI: 10.1159/000518067

  2 Insights on

  • Reduced Hospitalization Rate

  • High evidence
  • Clinical

  the admission rates were 30.9% and 9.8% in groups A and B, respectively. Additional L-carnitine significantly reduced the admission rate (p = 0.028).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  1,500 mg/day