L-Carnitine and Reduced Ulcer Size

• Interventions for treating leg ulcers in people with sickle cell disease.

  • 2021-01-09
  • Systematic Review · n = 198
  • The Cochrane database of systematic reviews 2021(1)
  • • Arturo J Martí-Carvajal
    • Jennifer M Knight-Madden
    • Maria José Martinez-Zapata

  • PubMed: 34559425
  • DOI: 10.1002/14651858.cd008394.pub4

  2 Insights on

  • Reduced Ulcer Size

  • High evidence
  • Clinical

  Three interventions reported on the change in ulcer size (arginine butyrate, RGD peptide, L-cartinine). Of these, only arginine butyrate showed a reduction of ulcer size compared with a control group...

  Effect

  Neutral

  Effect size

  Small

  Significant

  No