L-Carnosine protects against Oxaliplatin-induced peripheral neuropathy in colorectal cancer patients: A perspective on targeting Nrf-2 and NF-κB pathways.
- 2019-02
- RCT · n = 65
- Toxicology and applied pharmacology 365
- Rana Yehia
- Samira Saleh
- Hanan El Abhar
- Amr S Saad
- Mona Schaalan
- PubMed: 30592963
- DOI: 10.1016/j.taap.2018.12.015
- High evidence
- Clinical
Nrf-2 was increased (38.7%) as compared to Arm A
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 500 mg/day