L-Citrulline and Increased Fractional Exhaled Nitric Oxide

• Acute L-Citrulline Supplementation Increases Nitric Oxide Bioavailability but Not Inspiratory Muscle Oxygenation and Respiratory Performance.

  • 2021-09-22
  • Clinical Trial
  • Nutrients 13(10)
  • • Anastasios A Theodorou
    • Panagiotis T Zinelis
    • Vassiliki J Malliou
    • Panagiotis N Chatzinikolaou
    • Nikos V Margaritelis
    • Dimitris Mandalidis
    • Nickos D Geladas
    • Vassilis Paschalis

  • PubMed: 34684312
  • DOI: 10.3390/nu13103311

  5 Insights on

  • Increased Fractional Exhaled Nitric Oxide

  • High evidence
  • Rigorous Journal
  • Adults

  One-hour post-L-citrulline supplementation, exhaled NO• was significantly increased (19.2%; p < 0.05), and this increase was preserved until the end of the resistive breathing (16.4%; p < 0.05).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  6 g