L-Citrulline and Increased High-Density Lipoprotein Cholesterol

Doses used in studies

g/day: 3 (median 3, IQR 3–3) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

The impact of L-citrulline supplementation on glucose homeostasis, lipid profile, and some inflammatory factors in overweight and obese patients with type 2 diabetes: A double-blind randomized placebo-controlled trial.

2021-04-20
RCT · n = 54
Phytotherapy research : PTR 35(6)
- Samaneh Azizi
- Reza Mahdavi
- Majid Mobasseri
- Soghra Aliasgharzadeh
- Fatemeh Abbaszadeh
- Mehrangiz Ebrahimi-Mameghani

PubMed: 33876875
DOI: 10.1002/ptr.6997

10 Insights on

Increased High-Density Lipoprotein Cholesterol

High evidence
Clinical

Despite ... the increase in high-density lipoprotein cholesterol levels (p < .001) in the L-citrulline group, no significant differences were found for these parameters between the groups.

Effect: Neutral
Effect size: Small
Significant: No
Dose: 3 g/day