L-Citrulline and Reduced Augmentation Index at 75 bpm

• L-Citrulline supplementation attenuates aortic pulse pressure and wave reflection responses to cold stress in older adults.

  • 2022-03
  • RCT
  • Experimental gerontology 159
  • • Salvador J Jaime
    • Jessica Nagel
    • Arun Maharaj
    • Stephen M Fischer
    • Elizabeth Schwab
    • Christopher Martinson
    • Kim Radtke
    • Richard P Mikat
    • Arturo Figueroa

  • PubMed: 34990772
  • DOI: 10.1016/j.exger.2021.111685

  8 Insights on

  • Reduced Augmentation Index at 75 bpm

  • High evidence
  • Elderly

  AIx@75 (Δ-3.2 ± 7.2 vs. Δ2.2 ± 6.9%; P = 0.038)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  6 g/day