L-Citrulline and Reduced Augmented Pressure

• L-Citrulline supplementation attenuates aortic pulse pressure and wave reflection responses to cold stress in older adults.

  • 2022-03
  • RCT
  • Experimental gerontology 159
  • • Salvador J Jaime
    • Jessica Nagel
    • Arun Maharaj
    • Stephen M Fischer
    • Elizabeth Schwab
    • Christopher Martinson
    • Kim Radtke
    • Richard P Mikat
    • Arturo Figueroa

  • PubMed: 34990772
  • DOI: 10.1016/j.exger.2021.111685

  8 Insights on

  • Reduced Augmented Pressure

  • High evidence
  • Elderly

  AP (Δ-4 ± 4 vs. Δ2 ± 7 mmHg; P = 0.004) ... responses to the CPT were significantly attenuated following L-CIT supplementation vs. placebo.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  6 g/day