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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Glutamine and Reduced Organ Failure Severity

Doses used in studies

g/day: 7 (median 7, IQR 7–7) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

1 of 1 paper

Evaluation of the recovery after heart surgery following preoperative supplementation with a combination of beta-hydroxy-beta-methylbutyrate, L-arginine, and L-glutamine: a double-blind randomized placebo-controlled clinical trial.
- 2022-08-13
- RCT · n = 70
- Trials 23(1)
- - Mona Norouzi
  - Azadeh Nadjarzadeh
  - Majid Maleki
  - Sayyed Saeid Khayyatzadeh
  - Saeid Hosseini
  - Mehdi Yaseri
  - Hamed Fattahi
- PubMed: 35964137
- DOI: 10.1186/s13063-022-06621-1
5 Insights on
- Reduced Organ Failure Severity
- High evidence
- Clinical
Subjects in the Gln/Arg/HMB group had lower ... SOFA score (median [IQR] = 2 [2] vs. 5 [2]; P < 0.001)
Effect
Beneficial
Effect size
Large
Significant
Yes
Dose
7 g daily