L-ornithine supplementation in periodontitis treatment yields greater benefits than L-arginine after one year: Part II of a randomized controlled pilot study.
- 2025-09
- RCT · n = 75
- Complementary therapies in medicine 92
- Viktoriya I Shynkevych
- Svitlana V Kolomiiets
- Kristina O Udaltsova
- Igor P Kaidashev
- PubMed: 40614877
- DOI: 10.1016/j.ctim.2025.103202
- High evidence
- Clinical
After one year, patients who received L-arginine or L-ornithine exhibited a significant reduction of sites with periodontal pocket depth of 4-5 mm compared to PMPR (p < 0.0001)
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes