l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.
- 2018-10-10
- RCT
- Journal of clinical pharmacy and therapeutics 44(1)
- Ioannis Kyrgios
- Styliani Giza
- Eleni P Kotanidou
- Angeliki Kleisarchaki
- Vasiliki Rengina Tsinopoulou
- Vasiliki Rengina Tsinopoulou
- Anastasia Papadopoulou
- Anthi-Marina Markantonatou
- Eleni Kanellidou
- Anastasia Giannakou
- Assimina Galli-Tsinopoulou
- PubMed: 30306604
- DOI: 10.1111/jcpt.12765
- High evidence
- Clinical
Although anti-TPO levels were also decreased in the Se group, this change was not statistically different from that of the control group (Δ: -116.2 ± 68.4 vs +262.8 ± 255.5 IU/mL, P = 0.219)
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 200 μg daily