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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Selenomethionine and Reduced Anti-TPO Level

Doses used in studies

L-Selenomethionine · mcg/day: 200 (median 200, IQR 200–200) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis.
- 2007-07
- Clinical Trial · n = 80
- Thyroid : official journal of the American Thyroid Association 17(7)
- - Elias E Mazokopakis
  - John A Papadakis
  - Maria G Papadomanolaki
  - Antony G Batistakis
  - Triantafillos G Giannakopoulos
  - Eftichios E Protopapadakis
  - Emmanuel S Ganotakis
- PubMed: 17696828
- DOI: 10.1089/thy.2007.0040
2 Insights on
- Reduced Anti-TPO Level
- High evidence
- Clinical
In Group B, serum anti-TPO levels were increased by 4.8% (p < 0.0001) during the second 6-month period.
Effect
Neutral
Effect size
Small
Significant
Yes
Dose
200 microg Se in the form of l-selenomethionine orally for 6 months, then cessation for 6 months