Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the "SERENA study", a randomized, double-blind, placebo-controlled trial.
- 2019-05-25
- RCT
- Endocrine 66(3)
- G Mantovani
- A M Isidori
- C Moretti
- C Di Dato
- E Greco
- P Ciolli
- M Bonomi
- L Petrone
- A Fumarola
- G Campagna
- G Vannucchi
- S Di Sante
- C Pozza
- A Faggiano
- A Lenzi
- E Giannetta
- PubMed: 31129812
- DOI: 10.1007/s12020-019-01958-1
- High evidence
- Clinical
No differences were found in thyroid volume, echogenicity, quality of life, maternal/fetal complications.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 83 mcg/day