L-Serine and Reduced Knee Pain

• l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.

  • 2020-09
  • RCT · n = 120
  • The Journal of nutrition 150(9)
  • • Ikuko Sasahara
    • Akiko Yamamoto
    • Masamichi Takeshita
    • Yasuyo Suga
    • Katsuya Suzuki
    • Natsumi Nishikata
    • Michihiro Takada
    • Masaki Hashimoto
    • Tomoyuki Mine
    • Yasuo Kobuna
    • Kenji Nagao

  • PubMed: 32520991
  • DOI: 10.1093/jn/nxaa156

  5 Insights on

  • Reduced Knee Pain

  • High evidence
  • Large Human Trial
  • Clinical

  The JKOM scores at week 4 (11.7 ± 9.0 compared with 13.9 ± 7.9), week 8 (10.4 ± 7.9 compared with 13.1 ± 7.1), and week 12 (10.3 ± 7.4 compared with 13.8 ± 7.5) were lower in the active group (P ≤ 0.04).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  594 mg