L-Serine and Reduced Pain During Movement

• l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.

  • 2020-09
  • RCT · n = 120
  • The Journal of nutrition 150(9)
  • • Ikuko Sasahara
    • Akiko Yamamoto
    • Masamichi Takeshita
    • Yasuyo Suga
    • Katsuya Suzuki
    • Natsumi Nishikata
    • Michihiro Takada
    • Masaki Hashimoto
    • Tomoyuki Mine
    • Yasuo Kobuna
    • Kenji Nagao

  • PubMed: 32520991
  • DOI: 10.1093/jn/nxaa156

  5 Insights on

  • Reduced Pain During Movement

  • High evidence
  • Large Human Trial
  • Clinical

  BPI5D (pain during moving) at week 4 (P ≤ 0.028) and week 8 (P ≤ 0.019), respectively, and BPI5D was 23% better in the active group at week 12 (P = 0.007).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  594 mg