L-Serine and Reduced Seizure Frequency

• L-serine treatment in patients with GRIN-related encephalopathy: a phase 2A, non-randomized study.

  • 2024-02-21
  • Clinical Trial
  • Brain : a journal of neurology 147(5)
  • • Natalia Juliá-Palacios
    • Mireia Olivella
    • Mariya Sigatullina Bondarenko
    • Salvador Ibáñez-Micó
    • Beatriz Muñoz-Cabello
    • Olga Alonso-Luengo
    • Víctor Soto-Insuga
    • Deyanira García-Navas
    • Laura Cuesta-Herraiz
    • Patricia Andreo-Lillo
    • Sergio Aguilera-Albesa
    • Antonio Hedrera-Fernández
    • Elena González Alguacil
    • Rocío Sánchez-Carpintero
    • Fernando Martín Del Valle
    • Erika Jiménez González
    • Lourdes Cean Cabrera
    • Ines Medina-Rivera
    • Marta Perez-Ordoñez
    • Roser Colomé
    • Laura Lopez
    • María Engracia Cazorla
    • Montserrat Fornaguera
    • Aida Ormazabal
    • Itziar Alonso-Colmenero
    • Katia Sofía Illescas
    • Sol Balsells-Mejía
    • Rosanna Mari-Vico
    • Maria Duffo Viñas
    • Gerarda Cappuccio
    • Gaetano Terrone
    • Roberta Romano
    • Filippo Manti
    • Mario Mastrangelo
    • Chiara Alfonsi
    • Bruna de Siqueira Barros
    • Mathilde Nizon
    • Cathrine Elisabeth Gjerulfsen
    • Valeria L Muro
    • Daniela Karall
    • Fiona Zeiner
    • Silvia Masnada
    • Irene Peterlongo
    • Alfonso Oyarzábal
    • Ana Santos-Gómez
    • Xavier Altafaj
    • Ángeles García-Cazorla

  • PubMed: 38380699
  • DOI: 10.1093/brain/awae041

  8 Insights on

  • Reduced Seizure Frequency

  • Moderate evidence
  • Clinical

  and the frequency of seizures in one clinically affected child.

  Effect

  Beneficial

  Effect size

  Small

  Dose

  not stated