l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
- 2023-07
- RCT · n = 50
- Journal of affective disorders 333
- Ahmad Shamabadi
- Farnaz Kafi
- Melika Arab Bafrani
- Hassan Asadigandomani
- Fatemeh A Basti
- Shahin Akhondzadeh
- PubMed: 37084960
- DOI: 10.1016/j.jad.2023.04.029
- High evidence
- Clinical
A greater reduction in HDRS scores was observed in the l-theanine group from baseline to weeks 2, 4, and 6 (p-values = 0.02, 0.03, and 0.01, respectively).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 200 mg/d