L-Tryptophan and Increased Cholecystokinin Level

• Suppression of Energy Intake by Intragastric l-Tryptophan in Lean and Obese Men: Relations with Appetite Perceptions and Circulating Cholecystokinin and Tryptophan.

  • 2021-10
  • RCT · n = 13
  • The Journal of nutrition 151(10)
  • • Maryam Hajishafiee
    • Sina S Ullrich
    • Penelope Ce Fitzgerald
    • Michael Horowitz
    • Kylie Lange
    • Sally D Poppitt
    • Christine Feinle-Bisset

  • PubMed: 34255069
  • DOI: 10.1093/jn/nxab218

  6 Insights on

  • Increased Cholecystokinin Level

  • High evidence
  • Clinical

  Trp alone increased plasma CCK, Trp, and the Trp:LNAAs ratio (all P < 0.001), with no difference between groups.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  3 g (Trp-3) or 1.5 g (Trp-1.5)