L-Tryptophan and Reduced Hunger

• Suppression of Energy Intake by Intragastric l-Tryptophan in Lean and Obese Men: Relations with Appetite Perceptions and Circulating Cholecystokinin and Tryptophan.

  • 2021-10
  • RCT · n = 13
  • The Journal of nutrition 151(10)
  • • Maryam Hajishafiee
    • Sina S Ullrich
    • Penelope Ce Fitzgerald
    • Michael Horowitz
    • Kylie Lange
    • Sally D Poppitt
    • Christine Feinle-Bisset

  • PubMed: 34255069
  • DOI: 10.1093/jn/nxab218

  6 Insights on

  • Reduced Hunger

  • High evidence
  • Clinical

  hunger, fullness, and plasma CCK and amino acid concentrations were measured ... No significant effect on hunger was explicitly reported as such; however, the abstract does not mention a significant effect on hunger. Since the outcome was measured and no significant effect is indicated, it is treated as neutral.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  3 g (Trp-3) or 1.5 g (Trp-1.5)