N-Acetyl Cysteine and Improved Global Improvement of Symptoms (Clinician-Rated)

Doses used in studies

mg/day: 1,200 (median 1,200, IQR 1,200–1,200) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

N-Acetyl Cysteine as an Add-on Therapy is Useful in Treating Acute Lumbar Radiculopathy Caused by Disc Herniation: Results of a Randomized, Controlled Clinical Trial.

2023-11
RCT
Reviews on recent clinical trials 18(4)
- Bijan Heidari
- Zeinab-Alsadat Seyedian
- Maryam Mehrpooya
- Davoud Ahmadimoghaddam
- Mahtabalsadat Mirjalili
- Masood Ghiasian

PubMed: 37779397
DOI: 10.2174/0115748871250545230919055109

4 Insights on

Improved Global Improvement of Symptoms (Clinician-Rated)

High evidence
Clinical

more NAC-treated than placebo-treated patients achieved treatment success defined as 'very much' or 'much improved' on CGIC ... scales, and these differences reached a significant level (p-value = .011)

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 600 mg twice a day