Correlation of plasma lipidomic profiles with cardiometabolic disease in transfusion-dependent thalassemia patients with six-month N-acetylcysteine intervention: A prospective cohort study.
- 2025-12
- RCT
- Clinical biochemistry 140
- Yubin Lei
- Anik Forest
- Caroline Daneault
- Ying Liu
- Kostas Pantopoulos
- Adisak Tantiworawit
- Arintaya Phrommintikul
- Siriporn Chattipakorn
- Nipon Chattipakorn
- Christine Des Rosiers
- Gary Sweeney
- PubMed: 41135647
- DOI: 10.1016/j.clinbiochem.2025.111030
- High evidence
- Clinical
circulating diacylglycerophosphocholines PC(14:0_20:4) and cholesteryl ester CE 18:3 positively correlated with HRV, a clinical marker markedly improved in NAC-treated patients.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 600 mg oral daily