N-Acetyl Cysteine and Improved Mitochondrial Efficiency

• Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.

  • 2026-06-03
  • Review
  • Current nutrition reports 15(1)
  • • Jennifer A Kurtz
    • K Michelle Singleton
    • Ecaterina Vasenina
    • Ralf Jäger
    • Drew Gonzalez
    • Antonella Schwarz
    • Jonathan Howard
    • Jose Antonio

  • PubMed: 42234350
  • DOI: 10.1007/s13668-026-00776-y

  4 Insights on

  • Improved Mitochondrial Efficiency

  • Low evidence

  Antioxidants, glycine, N-acetylcysteine, and NAD⁺ precursors show potential benefits for mitochondrial efficiency, cellular stress responses, and cognitive performance; however, findings vary across populations and dosing strategies

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes