Efficacy and safety of N-acetylcysteine in patients with mild cognitive impairment undergoing exercise-based cardiac rehabilitation program: a randomized controlled trial.
- 2026-04-27
- RCT · n = 59
- Alzheimer's research & therapy 18(1)
- Damien Gallagher
- Yejin Kang
- Nathan Herrmann
- Alex Kiss
- Sandra E Black
- Paul Oh
- Susan Marzolini
- Jennifer S Rabin
- Ana Andreazza
- Joel Ramirez
- Fuqiang Gao
- Mark Rapoport
- Jinghan Jenny Chen
- Kate Survilla
- Danielle Vieira
- Ethan Mah
- Walter Swardfager
- Krista L Lanctôt
- PubMed: 42045982
- DOI: 10.1186/s13195-026-02062-z
- High evidence
- Clinical
with no significant differences between N-acetylcysteine and placebo (B=-0.04, 95% CI=-0.28 to 0.20, p=0.8) or in other cognitive domains.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 2400 mg/day