Safety and tolerability of topiramate and N-acetyl cysteine combination in individuals with alcohol use disorder: a 12 week, randomized, double-blind, pilot study.
- 2023-12-07
- RCT
- Alcohol and alcoholism (Oxford, Oxfordshire) 59(2)
- Nassima A-D Tiouririne
- Tevfik Kalelioglu
- Chamindi Seneviratne
- Xin-Qun Wang
- PubMed: 38069498
- DOI: 10.1093/alcalc/agad082
- High evidence
- Clinical
There was no difference in PHDD (P = 0.536) and in PDA over the entire study period (P = 0.892).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 1200 mg/day