N-Acetyl Cysteine and Increased H. pylori Eradication Rate

• The efficacy of adjuvant N acetyl cysteine for the eradication of H pylori infections: A systematic review and meta-analysis of randomized clinical trials.

  • 2022-03
  • Meta-Analysis · n = 1,167
  • Clinics and research in hepatology and gastroenterology 46(3)
  • • Dr Pritam Biswas
    • Dr Sukumar Tk

  • PubMed: 34775122
  • DOI: 10.1016/j.clinre.2021.101832

  1 Insight on

  • Increased H. pylori Eradication Rate

  • High evidence
  • Clinical

  the pooled outcomes of patients on adjuvant NAC+ standard eradication therapy noted an eradication rate of 76.1% (n=581) compared to the patients in standard eradication therapy with a rate of 72.18% (n=586), RR 1.17 [95% CI (0.99, 1.39); I2= 64%; p value=0.07].

  Effect

  Neutral

  Effect size

  Small

  Significant

  No