N-Acetyl Cysteine and Reduced Alcohol Consumption

Doses used in studies

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 1 study

Safety in these studies

cognitive adverse eventsNo significant difference
Cognitive adverse events were not significantly different between the treatment arms (P = 0.581).
from: Safety and tolerability of topiramate and N-acetyl cysteine combination in individuals wit
Overall tolerabilityReported
This pilot study indicates that combining NAC with TPM is overall safe, but the addition of NAC has no significant benefit over placebo in the incidence of TPM-related cognitive impairment, and alcohol drinking.
from: Safety and tolerability of topiramate and N-acetyl cysteine combination in individuals wit

1 of 1 paper

Safety and tolerability of topiramate and N-acetyl cysteine combination in individuals with alcohol use disorder: a 12 week, randomized, double-blind, pilot study.