Analgesic Efficacy of Bromelain and Bromelain Plus Turmeric for Pain Control After Orthodontic Separator Placement: A Triple-Blind Randomized Clinical Trial.
- 2025-04-01
- RCT · n = 135
- Clinical and experimental dental research 11(2)
- Shabnam Ajami
- Seyyed Hadi Hosseini
- Neda Babanouri
- Zahra Hashemi
- PubMed: 40260785
- DOI: 10.1002/cre2.70124
- High evidence
- Large Human Trial
- Clinical
At 48 h (T4), a significant difference was observed only in chewing function (p = 0.024), where patients in the Bromelain group reported higher pain scores than those in the Ibuprofen group.
- Effect
- Harmful
- Effect size
- Small
- Significant
- Yes
- Dose
- 200 mg (single dose)