Bromelain and Reduced Interleukin-12 Level

• Bromelain supplementation and inflammatory markers: A systematic review of clinical trials.

  • 2023-06
  • Systematic Review
  • Clinical nutrition ESPEN 55
  • • Irislene Costa Pereira
    • Eduardo Emanuel Sátiro Vieira
    • Lucillia Rabelo de Oliveira Torres
    • Felipe Cavalcanti Carneiro da Silva
    • João Marcelo de Castro E Sousa
    • Francisco Leonardo Torres-Leal

  • PubMed: 37202035
  • DOI: 10.1016/j.clnesp.2023.02.028

  2 Insights on

  • Reduced Interleukin-12 Level

  • High evidence
  • Mixed

  In most studies, supplementation with bromelain, isolated or in combined therapy, reduced inflammatory parameters.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  99.9 to 1200 mg/day (in combination therapy); 200 to 1050 mg/day (alone)