Lumbrokinase and Improved Barthel Index Score

• Therapeutic Potential of Lumbrokinase in Acute Ischemic Stroke: A Meta-Analysis of Efficacy and Safety.

  • 2025-09-04
  • Review · n = 35
  • Therapeutics and clinical risk management 21
  • • Elvan Wiyarta
    • Rakhmad Hidayat
    • Mohammad Kurniawan
    • Bryanna Infinita Laviashna Saputro
    • Indira Laksmi Maharani
    • Derren David Christian Homenta Rampengan
    • Lucia Callista Tanudharma
    • Raymond Rubianto Tjandrawinata

  • PubMed: 40933244
  • DOI: 10.2147/tcrm.s537232

  2 Insights on

  • Improved Barthel Index Score

  • Moderate evidence
  • Clinical

  Compared with supportive care alone, lumbrokinase adjunct therapy significantly improved Barthel Index scores (MD = 15.17; 95% CI: 14.60 to 15.74)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes