Nattokinase and Increased Total Cholesterol Level

• Nattokinase Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2023-08-15
  • Systematic Review · n = 546
  • Reviews in cardiovascular medicine 24(8)
  • • Xinmin Li
    • Junzi Long
    • Qian Gao
    • Mengyang Pan
    • Jing Wang
    • Fangjie Yang
    • Yasu Zhang

  • PubMed: 39076715
  • DOI: 10.31083/j.rcm2408234

  9 Insights on

  • Increased Total Cholesterol Level

  • High evidence

  Relatively low total dosage of nattokinase had a negative effect on blood total cholesterol (MD = 5.27, 95% CI: 3.74 to 6.81, p < 0.00001)

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes

  Dose

  relatively high total dosage