Nattokinase and Reduced Systolic Blood Pressure

• Nattokinase Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2023-08-15
  • Systematic Review · n = 546
  • Reviews in cardiovascular medicine 24(8)
  • • Xinmin Li
    • Junzi Long
    • Qian Gao
    • Mengyang Pan
    • Jing Wang
    • Fangjie Yang
    • Yasu Zhang

  • PubMed: 39076715
  • DOI: 10.31083/j.rcm2408234

  9 Insights on

  • Reduced Systolic Blood Pressure

  • High evidence

  Nattokinase supplementation significantly reduced systolic blood pressure (MD = -3.45, 95% CI: -4.37 to -2.18, p < 0.00001)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  relatively high total dosage