New evidence
Heat-killed probiotics boosted villus height and crypt depth in broiler intestines — but only at a higher dose, and growth performance didn't budge.
This is one of the first controlled trials to show that non-living probiotics can measurably alter gut structure in chickens, but with no prior human data on this specific preparation, it's a promising early signal — not a recommendation.
In a 300-broiler trial, a heat-killed mix of Bacillus subtilis and Lactobacillus plantarum at a higher dose increased villus height and crypt depth — markers of a healthier intestinal lining — compared to a lower dose or no supplement. However, the same birds showed no improvement in growth performance, and the study didn't specify the exact dose used, so the practical relevance for humans remains unknown.
Where this fits in the evidence
This is among the first studies we've indexed on Bacillus subtilis AB22 for Improved Intestinal Morphology — treat it as an early signal until more research accumulates.
The study
- Randomized Controlled Trial (RCT)
- n = 300
- 2025-09
- Veterinary and animal science
This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.