New evidence
A meta-analysis of 670 preterm infants linked bovine colostrum to a 24% lower risk of feeding intolerance — but the authors note the finding probably stems from unblinded trials, not the supplement itself.
This is the first pooled analysis on bovine colostrum for feeding intolerance, but the likely bias and null results on other outcomes mean it tells us more about how hard it is to study supplements in newborns than it does about a clear benefit.
Pooling results from multiple clinical trials showed that preterm infants given bovine colostrum had fewer episodes of feeding intolerance compared to those who did not receive it. However, the studies were not blinded (caregivers knew who got colostrum), which can skew results, and colostrum did not help infants reach full feeds sooner or prevent a dangerous gut condition called necrotizing enterocolitis. Any real benefit may be smaller than the headline number suggests, and adverse events were reported, so this is not a risk-free intervention.
Where this fits in the evidence
This is among the first studies we've indexed on Bovine Colostrum for Reduced Feeding Intolerance — treat it as an early signal until more research accumulates.
The study
- Systematic Review
- n = 670
- 2026-02-20
- Frontiers in nutrition
This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.